1、PDCD5（TFAR19） ：TFAR19, a novel apoptosis-related gene cloned from human leukemia cell line TF-1, could enhance apoptosis of some tumor cells induced by growth factor withdrawal. Liu H（刘洪涛）, Wang Y, Zhang Y, Song Q, Di C, Chen G, Tang J, Ma D.Biochem Biophys Res Commun. 1999 Jan 8;254(1):203-10.
2、PDCD10(TFAR15)：cDNA cloning and expression of an apoptosis-related gene, humanTFAR15 gene. Wang Y（王玉刚）, Liu H, Zhang Y, Ma D.Sci China C Life Sci. 1999 Jun;42(3):323-9.
3、NAIF1：Overexpression of the novel human gene, nuclear apoptosis-inducing factor 1, induces apoptosis. Lv B（吕冰峰）, Shi T, Wang X, Song Q, Zhang Y, Shen Y, Ma D, Lou Y.Int J Biochem Cell Biol. 2006;38(4):671-83
4、PTPIP51：PTPIP51, a novel 14-3-3 binding protein, regulates cell morphology and motility via Raf-ERK pathway.Yu C（于传飞）, Han W, Shi T, Lv B, He Q, Zhang Y, Li T, Zhang Y, Song Q, Wang L, Ma D.Cell Signal. 2008 Dec;20(12):2208-20
5、URP2SF：URP2SF, a FERM and PH domain containing protein, regulates NF-kappaB and apoptosis.Wang L, Deng W, Shi T, Ma D.Biochem Biophys Res Commun. 2008 Apr 18;368(4):899-906
6、DCUN1D3：DCUN1D3, a novel UVC-responsive gene that is involved in cell cycle progression and cell growth.Ma T（马腾）, Shi T, Huang J, Wu L, Hu F, He P, Deng W, Gao P, Zhang Y, Song Q, Ma D, Qiu X.Cancer Sci. 2008 Nov;99(11):2128-35
7、RNF122：RNF122: a novel ubiquitin ligase associated with calcium-modulating cyclophilin ligand. Peng Z（彭智）, Shi T, Ma D.BMC Cell Biol. 2010 Jun 17;11:41.
8、TMEM106A：Transmembrane protein 106A is silenced by promoter region hypermethylation and suppresses gastric cancer growth
by inducing apoptosis.Xu D（许东）, Qu L, Hu J, Li G, Lv P, Ma D, Guo M, Chen Y.J Cell Mol Med. 2014 Aug;18(8):1655-66
9、RNF121： Really interesting new gene finger protein 121 is a novel Golgi-localized membrane protein that regulates
apoptosis.Zhao Y（赵远波）, Hongdu B, Ma D, Chen Y.Acta Biochim Biophys Sin (Shanghai). 2014 Aug;46(8):668-74
1、TMEM74：TMEM74, a lysosome and autophagosome protein, regulates autophagy.Yu C, Wang L, Lv B, Lu Y, Zeng L, Chen Y, Ma D,
Shi T,Wang L.Biochem Biophys Res Commun. 2008 May 2;369(2):622-9
2、TMEM166（EVA1A）：TMEM166, a novel transmembrane protein, regulates cell autophagy and apoptosis. Wang L（王兰）, Yu C, Lu Y, He P, Guo J, Zhang C, Song Q, Ma D, Shi T, Chen Y.Apoptosis. 2007 Aug;12(8):1489-502.
3、TM9SF1：High-throughput functional screening for autophagy-related genes and identification of TM9SF1 as an autophagosome-inducing gene.He P（贺鹏飞）, Peng Z, Luo Y, Wang L, Yu P, Deng W, An Y, Shi T, Ma D. Autophagy. 2009 Jan;5(1):52-60
4、TMEM208：Transmembrane protein 208: a novel ER-localized protein that regulates autophagy and ER stress.Zhao Y（赵远波）, Hu J, Miao G, Qu L, Wang Z, Li G, Lv P, Ma D, Chen Y.PLoS One. 2013 May 14;8(5):e64228
5、EMC6：A novel ER-localized transmembrane protein, EMC6, interacts with RAB5A and regulates cell autophagy. Li Y, Zhao Y,
Hu J, Xiao J, Qu L, Wang Z, Ma D, Chen Y.Autophagy. 2013 Feb 1;9(2):150-63.
6、PHF23 ：PHF23 (plant homeodomain finger protein 23) negatively regulates cell autophagy by promoting ubiquitination and
degradation of E3 ligase LRSAM1.Wang Z, Hu J, Li G, Qu L, He Q, Lou Y, Song Q, Ma D, Chen Y.Autophagy. 2014 Dec 2;10(12):2158-70
1、CKLF（CCR4配体）：Molecular cloning and characterization of chemokine-like factor 1 (CKLF1), a novel human cytokine with unique structure and potential chemotactic activity.Han W, Lou Y,
Tang J, Zhang Y, Chen Y, Li Y, Gu W, Huang J, Gui L, Tang Y, Li F, Song Q, Di C, Wang L, Shi Q, Sun R, Xia D, Rui M,
Tang J, Ma D.Biochem J. 2001 Jul 1;357(Pt 1):127-35.
2、PSMP(CCR2配体）：PC3-secreted microprotein is a novel chemoattractant protein and functions as a high-affinity ligand for CC chemokine receptor2.Pei X, Sun Q, Zhang Y, Wang P, Peng X, Guo C, Xu E, Zheng Y, Mo X, Ma J,
Chen D, Zhang Y, Zhang Y, Song Q, Guo S, Shi T, Zhang Z, Ma D, Wang 3、Y.J Immunol. 2014 Feb 15;192(4):1878-86
3、FAM19A4（FPR1配体）：FAM19A4 is a novel cytokine ligand of formyl peptide receptor 1 (FPR1) and is able to promote the
migration and phagocytosis of macrophages.Wang W, Li T, Wang X, Yuan W, Cheng Y, Zhang H, Xu E, Zhang Y, Shi S, Ma D,
Han W.Cell Mol Immunol. 2014 Aug 11. doi: 10.1038/cmi.2014.61. [Epub ahead of print]
4. CKLF1衍生肽（作用受体CCR4、CCR3）：
Two c-terminal peptides of human CKLF1 interact with chemokine receptor CCR4. Ying Wang, Yingmei Zhang, Wenling Han, Dan Li, Linjie Tian, Caihua Yin,
Dalong Ma. Int.J.Biochem.Cell.Biol. 2008; 40: 909-919.
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CKLF超家族
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CMTM1-8（CKLF-like Marvel transmembrane domain containing 1-8）Identification of eight genes encoding chemokine like factor superfamily members 1-8(CKLFSF1-8) by in silico cloning and experimental validation. Han W, Ding P, Xu M, Wang L, Rui M, Shi S, Liu Y, Zheng Y,
Chen Y, Yang T, Ma D.Genomics. 2003 Jun;81(6):609-17.
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CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas
and inhibits tumor cell growth through inducing apoptosis.Wang Y, Li J, Cui Y, Li T, Ng KM, Geng H, Li H,
Shu XS, Li H, Liu W, Luo B, Zhang Q, Mok TS, Zheng W, Qiu X, Srivastava G, Yu J, Sung JJ, Chan AT, Ma D,
Tao Q, Han W.Cancer Res. 2009 Jun 15;69(12):5194-201
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CMTM4：Identification and characterization of CMTM4, a novel gene with inhibitory effects on HeLa cell growth through
Inducing G2/M phase accumulation.Plate M, Li T, Wang Y, Mo X, Zhang Y, Ma D, Han W.Mol Cells. 2010 Apr;29(4):355-61
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CMTM5 exhibits tumor suppressor activities and is frequently silenced by methylation in carcinoma cell lines.
Shao L, Cui Y, Li H, Liu Y, Zhao H, Wang Y, Zhang Y, Ng KM, Han W, Ma D, Tao Q.Clin Cancer Res. 2007 Oct 1;13(19):5756-62.
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CMTM8：Regulation of EGF receptor signaling by the MARVEL domain-containing protein CKLFSF8.Jin C, Ding P, Wang Y, Ma D.FEBS Lett. 2005 Nov 21;579(28):6375-82.
1、CCDC134：CCDC134, a novel secretory protein, inhibits activation of ERK and JNK, but not p38 MAPK.Huang J, Shi T, Ma T,
Zhang Y,Ma X, Lu Y, Song Q, Liu W, Ma D, Qiu X.Cell Mol Life Sci. 2008 Jan;65(2):338-49.
2、CTRP4：Identification of C1qTNF-related protein 4 as a potential cytokine that stimulates the STAT3 and NF-κB pathways and promotes cell survival in human cancer cells.Li Q, Wang L, Tan W, Peng Z, Luo Y, Zhang Y, Zhang G, Na D,
Jin P, Shi T, Ma D, Wang L.Cancer Lett. 2011 Sep 28;308(2):203-14.
3、VSTM1-v2：VSTM1-v2, a novel soluble glycoprotein, promotes the differentiation and activation of Th17 cells.Guo X, Zhang Y,
Wang P, Li T, Fu W, Mo X, Shi T, Zhang Z, Chen Y, Ma D, Han W.Cell Immunol. 2012 Jul-Aug;278(1-2):136-42
